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Pharmaceutical and Biomedical Research، جلد ۱۰، شماره ۱، صفحات ۷۳-۷۸
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Acute Efavirenz Intoxication in a 16-year-old HIV Negative Girl: A Case Report and Literature Review |
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| چکیده انگلیسی مقاله |
Background: There are only rare case reports that revealed the efavirenz (EFV) toxicity.
Case Report: This study presents an acute intoxication with 12 g of efavirenz in a 16-year-old healthy girl whose main problem was dose-dependent neurotoxicity. No other serious EFV-related side effects were seen. Previous serious side effects of EFV were observed in HIV-infected patients who underwent long-term combination drug therapy.
Conclusion: Accordingly, in terms of the key clinical messages, serious adverse effects of efavirenz are expected to be observed in long-term use in combination with other antiretroviral drugs. |
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| کلیدواژه‌های انگلیسی مقاله |
Efavirenz, Intoxication, Neurotoxicity, Human immunodeficiency virus, Toxicology |
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| نویسندگان مقاله |
| Minoo Moghimi
Department of Clinical Pharmacy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
| Zahra Nekoukar
Department of Clinical Pharmacy, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
| Navid Khosravi
Department of Emergency Medicine, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
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| نشانی اینترنتی |
http://pbr.mazums.ac.ir/browse.php?a_code=A-10-931-1&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
داروسازی بالینی |
| نوع مقاله منتشر شده |
گزارش مورد |
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