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Pharmaceutical and Biomedical Research، جلد ۱۰، شماره ۱، صفحات ۷۹-۸۲
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Investigating the Excessive Sweating Induced by Aripiprazole: Two Case Reports |
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| چکیده انگلیسی مقاله |
Background: Many drugs, including antipsychotics, cause an adverse effect, such as excessive sweating (hyperhidrosis). Hyperhidrosis occurs by drugs that act on the thermoregulatory centers in the hypothalamus, spinal, and sympathetic ganglia or on the endocrine system.
Case Report: This study reports two patients who developed hyperhidrosis while taking aripiprazole. A 38-year-old woman who had a diagnosis of obsessive-compulsive disorder and a 17-year-old boy who developed multiple motor tics continued to take aripiprazole even though they had hyperhidrosis. The dosage of aripiprazole was adjusted to reduce diaphoresis.
Conclusion: Besides the potential risks of dehydration, electrolyte depletion, and hypothermia, hyperhidrosis may be a distressing and embarrassing symptom that, if not addressed properly, can promote noncompliance with the medication. Therefore, it is imperative to create awareness of this unusual potential adverse effect of aripiprazole. |
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| کلیدواژه‌های انگلیسی مقاله |
Aripiprazole, Hyperhidrosis, Sweating, Adverse drug event |
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| نویسندگان مقاله |
| Seyed Hamzeh Hosseini
Psychosomatics Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
| Hamed Ghazvini
Department of Neuroscience, School of Advanced Technologies in Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
| Seyedeh Masoumeh Seyedhosseini Tamijani
Psychiatry and Behavioral Sciences Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran.
| Raheleh Rafaiee
Department of Neuroscience, School of Advanced Technologies in Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
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| نشانی اینترنتی |
http://pbr.mazums.ac.ir/browse.php?a_code=A-10-1231-1&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
داروسازی بالینی |
| نوع مقاله منتشر شده |
گزارش مورد |
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