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تحقیقات دامپزشکی، جلد ۶۳، شماره ۳، صفحات ۲۱۵-۲۲۰
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| عنوان فارسی |
بررسی اثر تجویز خوراکی آیور مکتین بر برخی پارامترهای هماتولوژی و بیوشیمیایی خون الاغ (اکووس آسینوس) |
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| چکیده فارسی مقاله |
Five healthy adult male Iranian donkeys (Equus asinus) were selected and Ivermectin (0.2, 0.6 and 0.9 mglkg, orally at different times) for 14 days was administered. Before dosing, control blood samples were taken on day O. Blood samples were taken on days 1,2,3,7 and 14 following ivermectin administration at different doses. The results showed that the activity of serumAST and LDH increased on days 7 and 14 following ivermectin (0.2, 0.6 and 0.9 mglkg, orally) administration (p< 0.05). ALP activity and BUN concentration increased significantly on day 14 following ivermectin (0.2, 0.6 and 0.9 mglkg, orally) administration (p< 0.05). Changes of ablumin, creatinin,glucose, total protein, Phosphorous and calcium concentrations and hemoglobin, PCV, MCH, MCHC, MCV and percentages of neutrophils, eosinophils, monocytes, lymphocytes and platelet numbers were not significant (p>0.05). As it was shown in short term, no abnormal clinical and laboratory findings were detected following different oral doses of ivermectin and it seems that the drug can be safely administered to this species |
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| کلیدواژههای فارسی مقاله |
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| عنوان انگلیسی |
EFFECT OF ORALLY ADMINISTERED IVERMECTIN ON SOME BLOOD HAEMATOLOGICALAND BIOCHEMICAL FACTORS IN DONKEYS (EQQU SASINUS) |
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| چکیده انگلیسی مقاله |
Five healthy adult male Iranian donkeys (Equus asinus) were selected and Ivermectin (0.2, 0.6 and 0.9 mglkg, orally at different times) for 14 days was administered. Before dosing, control blood samples were taken on day O. Blood samples were taken on days 1,2,3,7 and 14 following ivermectin administration at different doses. The results showed that the activity of serumAST and LDH increased on days 7 and 14 following ivermectin (0.2, 0.6 and 0.9 mglkg, orally) administration (p< 0.05). ALP activity and BUN concentration increased significantly on day 14 following ivermectin (0.2, 0.6 and 0.9 mglkg, orally) administration (p< 0.05). Changes of ablumin, creatinin,glucose, total protein, Phosphorous and calcium concentrations and hemoglobin, PCV, MCH, MCHC, MCV and percentages of neutrophils, eosinophils, monocytes, lymphocytes and platelet numbers were not significant (p>0.05). As it was shown in short term, no abnormal clinical and laboratory findings were detected following different oral doses of ivermectin and it seems that the drug can be safely administered to this species |
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| کلیدواژههای انگلیسی مقاله |
biochemistrya, Blood, donkey., haematology, Ivermectin |
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| نویسندگان مقاله |
خلیل بدیعی | گروه علوم درمانگاهی دانشکده دامپزشکی شیراز
فرانک ابنا رودحله | abna rodhele گروه علوم درمانگاهی دانشکده دامپزشکی شیراز
اردوان نوروزی اصل | noroozi asl دانشکده دامپزشکی دانشگاه آزاد اسلامی کازرون سازمان اصلی تایید شده: دانشگاه آزاد اسلامی کازرون (Islamic azad university of kazerun)
مهرداد پورجعفر | گروه علوم درمانگاهی دانشکده دامپزشکی شیراز
بهروز نیک احوال | nik احوال گروه دامپزشکی دانشگاه آزاد اسلامی واحد بجنورد سازمان اصلی تایید شده: دانشگاه آزاد اسلامی بجنورد (Islamic azad university of bojnourd)
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| نشانی اینترنتی |
http://jvr.ut.ac.ir/article_23722_9a23389f991f4879498b2926b1142e5e.pdf |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/699/article-699-311511.pdf |
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| زبان مقاله منتشر شده |
fa |
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