تحقیقات دامپزشکی، جلد ۶۳، شماره ۳، صفحات ۲۱۵-۲۲۰

عنوان فارسی بررسی اثر تجویز خوراکی آیور مکتین بر برخی پارامترهای هماتولوژی و بیوشیمیایی خون الاغ (اکووس آسینوس)
چکیده فارسی مقاله Five healthy adult male Iranian donkeys (Equus asinus) were selected and Ivermectin (0.2, 0.6 and 0.9 mglkg, orally at different times) for 14 days was administered. Before dosing, control blood samples were taken on day O. Blood samples were taken on days 1,2,3,7 and 14 following ivermectin administration at different doses. The results showed that the activity of serumAST and LDH increased on days 7 and 14 following ivermectin (0.2, 0.6 and 0.9 mglkg, orally) administration (p< 0.05). ALP activity and BUN concentration increased significantly on day 14 following ivermectin (0.2, 0.6 and 0.9 mglkg, orally) administration (p< 0.05). Changes of ablumin, creatinin,glucose, total protein, Phosphorous and calcium concentrations and hemoglobin, PCV, MCH, MCHC, MCV and percentages of neutrophils, eosinophils, monocytes, lymphocytes and platelet numbers were not significant (p>0.05). As it was shown in short term, no abnormal clinical and laboratory findings were detected following different oral doses of ivermectin and it seems that the drug can be safely administered to this species
کلیدواژه‌های فارسی مقاله

عنوان انگلیسی EFFECT OF ORALLY ADMINISTERED IVERMECTIN ON SOME BLOOD HAEMATOLOGICALAND BIOCHEMICAL FACTORS IN DONKEYS (EQQU SASINUS)
چکیده انگلیسی مقاله Five healthy adult male Iranian donkeys (Equus asinus) were selected and Ivermectin (0.2, 0.6 and 0.9 mglkg, orally at different times) for 14 days was administered. Before dosing, control blood samples were taken on day O. Blood samples were taken on days 1,2,3,7 and 14 following ivermectin administration at different doses. The results showed that the activity of serumAST and LDH increased on days 7 and 14 following ivermectin (0.2, 0.6 and 0.9 mglkg, orally) administration (p< 0.05). ALP activity and BUN concentration increased significantly on day 14 following ivermectin (0.2, 0.6 and 0.9 mglkg, orally) administration (p< 0.05). Changes of ablumin, creatinin,glucose, total protein, Phosphorous and calcium concentrations and hemoglobin, PCV, MCH, MCHC, MCV and percentages of neutrophils, eosinophils, monocytes, lymphocytes and platelet numbers were not significant (p>0.05). As it was shown in short term, no abnormal clinical and laboratory findings were detected following different oral doses of ivermectin and it seems that the drug can be safely administered to this species
کلیدواژه‌های انگلیسی مقاله biochemistrya, Blood, donkey., haematology, Ivermectin

نویسندگان مقاله خلیل بدیعی |
گروه علوم درمانگاهی دانشکده دامپزشکی شیراز

فرانک ابنا رودحله | abna rodhele
گروه علوم درمانگاهی دانشکده دامپزشکی شیراز

اردوان نوروزی اصل | noroozi asl
دانشکده دامپزشکی دانشگاه آزاد اسلامی کازرون
سازمان اصلی تایید شده: دانشگاه آزاد اسلامی کازرون (Islamic azad university of kazerun)

مهرداد پورجعفر |
گروه علوم درمانگاهی دانشکده دامپزشکی شیراز

بهروز نیک احوال | nik احوال
گروه دامپزشکی دانشگاه آزاد اسلامی واحد بجنورد
سازمان اصلی تایید شده: دانشگاه آزاد اسلامی بجنورد (Islamic azad university of bojnourd)


نشانی اینترنتی http://jvr.ut.ac.ir/article_23722_9a23389f991f4879498b2926b1142e5e.pdf
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