Journal of Research in Orthopedic Science، جلد ۹، شماره ۳، صفحات ۱۵۷-۱۶۴

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عنوان انگلیسی Comparing the Effects of Vitamins C and D in Preventing Complex Regional Pain Syndrome After Distal Radius Fracture Treatment
چکیده انگلیسی مقاله
Background: The inflammatory response following trauma is the possible pathophysiology of complex regional pain syndrome (CRPS) I, caused by the release of pro-inflammatory factors and neuropeptides. Vitamins C and D are two antioxidants that can effectively prevent the occurrence of CRPS I.
Objectives: The primary aim of this study was to compare the effectiveness of vitamins C and D in preventing the occurrence of CRPS following the fixation of distal radius fractures.
Methods: The study was performed from January 1, 2018 to the end of December 2019. Patients who had fractured distal radius were candidates for external fixation and PCP. The patients were divided into three groups: 1) Receiving 500 mg of vitamin C daily for 50 days, 2) Receiving an oral dose of vitamin D of 5000 IU weekly for 50 days, and 3) Receiving no complementary medicine (control group). 
Results: Of the 150 fractures, 62 type C3, 56 type C2, and 32 type C1 were observed, constituting 41.3%, 37.3%, and 21.3% of the total. During the two follow-up sessions, CRPS occurred in 28 patients (18.7%). Among the 28 patients mentioned, 14 patients (50%) belonged to group C, 8 patients (28.6%) belonged to group B, and 6 patients (21.4%) belonged to group A. 
Conclusion: The use of vitamins C and D reduced the incidence of CRPS in patients with distal radius fractures. Also, the use of these vitamins was significantly effective in improving CRPS and reducing pain and ROM limitation. 
کلیدواژه‌های انگلیسی مقاله Distal radius fracture, Vitamin C, Vitamin D, Complex regional pain syndrome (CRPS)

نویسندگان مقاله | Adel Ebrahimpour
Department of Orthopedic Surgery, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.


| Farsad Biglari
Department of Orthopedic Surgery, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.


| Amir Sabaghzadeh
Department of Orthopedic Surgery, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.


| Saber Barazandeh Rad
Department of Orthopedic Surgery, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.


| Mehrdad Sadighi
Department of Orthopedic Surgery, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.


| Tohid Moradian
Department of Orthopedic Surgery, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.


| Meisam Jafari Kafiabadi
Department of Orthopedic Surgery, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.



نشانی اینترنتی http://jros.iums.ac.ir/browse.php?a_code=A-10-987-2&slc_lang=en&sid=1
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