، جلد ۱۹، شماره ۱، صفحات ۱۴۵-۱۵۶

عنوان فارسی اثرات فیزیولوژیکی و بافتی برخی از مکمل های غذایی و دوپینگ در موش های صحرایی نر
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عنوان انگلیسی Physiological and Histological Effects of Some Nutritional Supplements and Doping in Male Rats
چکیده انگلیسی مقاله Background: Nutritional supplements (NSs) are nutritional components, not foods such as protein, that are commercially available and consumed in addition to the diet.
Objectives: We aim to investigate the impact of NSs and testosterone hormone used in sports training centers on male reproductive hormones like spermatogenesis-stimulating hormone (SSH), interstitial cell-stimulating hormone (ICSH), testosterone hormone, and cortisol, as well as assessing histological changes in the testis of exercising male rats.
Methods: The study involved 80 rats divided into 8 groups. The first group was the control, while the second group was subjected to exercise. The third group received NS, the fourth group was injected with a testosterone blend, and the fifth group received NS and a testosterone blend. The sixth group was given NS with exercising, the seventh group was injected with a testosterone blend with exercising, and the eighth group was given NS and a testosterone blend with exercise.
Results: There was a significant increase in SSH, ICSH, cortisol, and testosterone hormone concentration in the group treated with NS and injected with testosterone blend compared to the rest of the groups. The results of histological examinations showed abnormal seminiferous tubules with an increase in diameter and thickness of the spermatogenic cell layer. Also, the seminiferous tubules were broadly separated from each other, and cell necrosis for rats treated with NS and testosterone blend compared to the rest of the groups revealed normal shape and arrangement of testicular cells. Exercise has positively reversed the negative effects of dietary supplementation and testosterone on male sex hormone levels and cortisol, in addition to reducing the negative effects on testicular tissue of male rats.
Conclusion: Treatment with NS and testosterone blend had adverse effects on the concentration of some hormones. There were also some histological changes in the testis. 
کلیدواژه‌های انگلیسی مقاله Cortisol,rats,Sports training,Spermatogenesis-stimulating hormone (SSH),Testosterone

نویسندگان مقاله Omar N Sultan |
Department of Biology, College of Sciences, University of Mosul, Mosul, Iraq.

Muntaha Mahmoud Al-Kattan |
Department of Biology, College of Sciences, University of Mosul, Mosul, Iraq.


نشانی اینترنتی https://ijvm.ut.ac.ir/article_100615_a23187cce2bd24983fde90c026b0930c.pdf
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