| چکیده انگلیسی مقاله |
Abstract
Introduction: Infection at the surgical site is a devastating complication of spinal surgery, and proper prevention is the key to the success of these surgeries. Any incidence of surgical site infection (SSI) can increase the cost of care by up to four times the cost of primary spinal surgery. The use of prophylactic antibiotics to reduce SSI has been reported in studies.
Materials and Methods: The cohort study included patients who underwent spinal cord surgery at our center between 2019 and 2021. These patients were randomly assigned to two groups for prophylaxis: one group received antibiotics based on the routine protocol, while the other group received antibiotics according to the new protocol. All patients were evaluated for surgical site infection (SSI) starting from two weeks after the surgery.
Results: A total of 80 patients underwent spinal cord surgery, with 40 patients in each group (upgraded protocol and common protocol). The gender distribution was equal, with 20 male and 20 female participants in each group. The mean age of patients in the upgraded protocol group was 38.1 ± 21.2 years, while in the common protocol group it was 38.2 ± 20.8 years, showing no significant difference. There was no significant association between patients' sex and age group with surgical site infection (SSI). Among the patients in the common protocol group, 4 patients (10%) developed an infection at the surgical site. In contrast, in the upgraded protocol group, only 1 patient (2.5%) had a positive culture infection, and 1 patient (2.5%) had a negative culture. This difference in SSI between the two groups following the upgraded and common protocols was statistically significant.
Conclusion: The study found that patients in the upgraded protocol group had significantly lower rates of surgical site infection (SSI) compared to patients in the standard protocol group. Factors such as diabetes mellitus, increased length of ICU stays, and urinary catheterization were identified as influencing SSI. However, age, gender, corticosteroid use, smoking, emergency or elective surgery, bleeding volume, chemotherapy and radiotherapy, and dura opening were not found to be associated with SSI.
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