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Caspian Journal of Neurological Sciences، جلد ۲، شماره ۷، صفحات ۴۱-۴۸
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عنوان فارسی |
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چکیده فارسی مقاله |
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کلیدواژههای فارسی مقاله |
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عنوان انگلیسی |
Peripheral Neuro Electrodiagnostic Abnormalities in Patients with Multiple Sclerosis: A Cross Sectional Study |
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چکیده انگلیسی مقاله |
Background: Multiple sclerosis (MS) is known to affect essentially the central nervous system; however, peripheral nerve involvement, as an additional cause of disability, has been recently noticed. Objectives: This study was aimed to perform detailed electrodiagnostic assessments in MS patients to evaluate peripheral nervous system involvement. Materials and Methods: A total of eighty MS patients were evaluated for probable peripheral nerves involvement in a cross sectional study from August 2012 to August 2013.Patients with evidence of radiculopathy, diabetes, uremia, and anemia or cobalamin deficiency had been excluded. Clinical disability was ascertained by applying Expanded Disability Status Scale (EDSS) score. All electrodiagnostic assessment was performed by a single expert operator. Demographic parameters and paraclinical findings including MRI plaques were recorded. The data were analyzed in SPSS version 19applying the paired t-test and Mann-Whitney U test. Results: The sural nerves showed the most consistent finding of abnormal conduction velocity (30%). The most frequent amplitude disturbance was observed in the peroneal nerves (10%). We did not find a significant association between abnormal findings and EDSS or MRI plaques (p< 0.05). Patients with raised latency of the sensory nerves were younger than those with normal figures (p< 0.05). Also, patients with prolonged disease were more likely to show peripheral nerve disturbances (p< 0.05). Conclusion: Peripheral nerve involvement was seen in MS patients, without significant relationship with physical disability and MRI plaques. On the other hand, disease duration, age and male gender were associated with peripheral nerve abnormalities. |
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کلیدواژههای انگلیسی مقاله |
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نویسندگان مقاله |
مرتضی سعیدی | morteza saeidi associate professor of neurology, department of neurology, school of medicine, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
سمانه رفتاری | samaneh raftari neurologist, department of neurology, school of medicine, mashhad university of medical sciences, mashhad, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
سید علی رودباری | seyed ali roudbary associate professor, neurology department of poursina hospital, guilan university of medical sciences, rasht, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی گیلان (Guilan university of medical sciences)
فریبرز رضایی طلب | fariborz rezaeitalab assistant professor of neurology, department of neurology, school of medicine, mashhad university of medical sciences, mashhad, iran; rezaeitalabf@mums.ac.ir
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)
حمیدرضا حاتمیان | hamidreza hatamian professor, department of neurology, poursina hospital, guilan university of medical sciences, rasht, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی گیلان (Guilan university of medical sciences)
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نشانی اینترنتی |
http://cjns.gums.ac.ir/browse.php?a_code=A-10-32-55&slc_lang=en&sid=en |
فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/1782/article-1782-347274.pdf |
کد مقاله (doi) |
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زبان مقاله منتشر شده |
en |
موضوعات مقاله منتشر شده |
تخصصی |
نوع مقاله منتشر شده |
پژوهشی |
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