Basic and Clinical Neuroscience، جلد ۱۶، شماره ۲، صفحات ۰-۰

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عنوان انگلیسی Effectiveness of Low-Frequency rTMS and CBT in Reducing Symptoms Severity and Improving Cognitive Flexibility in Adults with OCD: A Clinical Tria
چکیده انگلیسی مقاله
Background: This study aims to assess and compare the effects of low-frequency (LF) cognitive-behavioral therapy (CBT) and repetitive transcranial magnetic stimulation (rTMS) on symptoms and cognitive flexibility of adults with OCD.
Methods: This is a randomized clinical trial conducted on 24 people with OCD in Zanjan, Iran in two groups of CBT (n=12) and rTMS (n=12). The CBT with exposure and response prevention was presented at 20 sessions. The 1-Hz rTMS was delivered at 100 of resting MT using an 8-shaped coil over the right dorsolateral prefrontal cortex (F4) for 2 weeks at 10 sessions. They completed the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) and the Cognitive Flexibility Inventory before, immediately, and one month after the intervention. Collected data were analyzed in SPSS v.22 software.
Results: Results showed a significant difference between the two groups in the severity of OCD symptoms (obsessions and compulsions) immediately after intervention (p<0.001), where higher reductions were observed in the CBT group. There was no significant difference between the two groups in cognitive flexibility (p>0.05). No significant difference was found between the groups in any study variables one month after interventions.
Conclusion: There is a significant difference between CBT and LF rTMS techniques in reducing the severity of OCD symptoms, while there is no difference between them in improving cognitive flexibility of patients with OCD.
کلیدواژه‌های انگلیسی مقاله Obsessive compulsive disorder, Cognitive behavioral therapy, Repetitive transcranial magnetic stimulation, Cognitive flexibility ​​​​​​

نویسندگان مقاله | Arash Fazeli
Department of Psychiatry, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.


| Ahmad Zolghadriha
Department of Psychiatry, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.


| Reza Pirzeh
Department of Psychiatry, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.


| Shokoufe Ramezani
Department of Educational Sciences, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran.


| Mohsen Dadashi
Department of Clinical Psychology, Social Determinants of Health Research Center, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.



نشانی اینترنتی http://bcn.iums.ac.ir/browse.php?a_code=A-10-5047-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Clinical Neuroscience
نوع مقاله منتشر شده Original
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