|
|
، جلد ۱۸، شماره Special Issue، صفحات ۶۶۱-۶۷۲
|
|
|
| عنوان فارسی |
سنسور الکتروشیمیایی مبتنی بر اتر کراون پلیمری Thia برای تعیین کاربامازپین و افدرین |
|
| چکیده فارسی مقاله |
|
|
| کلیدواژه‌های فارسی مقاله |
|
|
| عنوان انگلیسی |
Electrochemical Sensor Based on Crafted Thia Polymeric Crown Ether for Determination of Carbamazepine and Ephedrine |
|
| چکیده انگلیسی مقاله |
Background: Direct analysis methods are considered some of the best and easiest tools to quickly determine the amount of active drug in some pharmaceutical preparations. Objectives: In this study, an ion electrode is prepared to determine the concentration of a sample of ephedrine (Eph) and carbamazepine (CBZ) in the medicines produced by some companies directly.
Methods: CBZ and Eph drugs ion-selective electrode (ISE) based on Thia polymeric crown ether (SPCE-CZB and SPCE-Eph) as membrane carrier in polyvinyl chloride (PVC) matrix was successfully fabricated for the determination of CBZ and Eph drugs.
Results: The electrode exhibited a liner Nernstian slope response over the range of 1×10-1 to 1×10-6 M, and 1×10-5 to 1×10-1 with a slope of 28 and 33±2 mV per decade charge, respectively, by using dimethyl phthalate plasticizer and a detection limit of 1×10-9 M. The response time of the sensor was 10 s. The ISE showed a greater preference for CBZ and Eph over other drugs with good precision.
Conclusion: The selectivity coefficients of some drugs ranged from 1×10-5 to 1×10-1. Meanwhile, SPCE-CZB (ISE) was successfully used as an indicator electrode for the potentiometric determination of the CBZ drug pharmaceutical formulas. |
|
| کلیدواژه‌های انگلیسی مقاله |
Carbamazepine (CBZ),Ephedrine (Eph),Ion-selective electrode (ISE),Thia polymeric crown ether,Potentiometric sensor |
|
| نویسندگان مقاله |
Hussain Najam |
Department of Medical Laboratory Technique, Altoosi University College, Najaf, Iraq.
Abdullah Shakir |
Najaf Technical Institute, Al-Furat Al-Awsat Technical University, Najaf, Iraq.
Sara Muhsan |
Department of Chemistry, College of Medical Technology, The Islamic University, Najaf, Iraq.
Fadhil Faez Sead |
Department of Chemistry, College of Medical Technology, The Islamic University, Najaf, Iraq.
Hussein Jasim Mohammed |
Department of Chemistry, Faculty of Science, University of Kufa, Iraq.
|
|
| نشانی اینترنتی |
https://ijvm.ut.ac.ir/article_100117_b17eb4b4828ace0d3040c81da637c7d1.pdf |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
|
| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
|
| نوع مقاله منتشر شده |
|
|
|
|
برگشت به:
صفحه اول پایگاه |
نسخه مرتبط |
نشریه مرتبط |
فهرست نشریات
|