سامانه اطلاعات پژوهشی ایران - NRIP Journals

جمعه 13 تیر 1404


Auditory and Vestibular Research، جلد ۲۴، شماره ۲، صفحات ۹۲-۹۷


عنوان فارسی

چکیده فارسی مقاله

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عنوان انگلیسی	Creatine supplement affects cervical vestibular myogenic potentials in healthy volunteers

چکیده انگلیسی مقاله	Background and Aim: Creatine is an energy-supplying protein in neuromuscular system with a protective role in relieving neurological symptoms. Since the enzymes and other mechanism involved in the conversion of creatine in the inner ear and vestibular nuclei are found in abundance, the aim of this study was to measure the effects of creatine on cervical vestibular evoked myogenic potentials (cVEMP) parameters. Methods: In this double-blind study, 35 healthy males aged 20-25 were randomly divided into an interventional (given creatine monohydrate) and a placebo groups (given maltodextrin). Participants received 5 g of dissolved powders in 250 ml water 4 times/days for 5 consecutive days. Cervical myogenic potentials were recorded before and after intervention with 500 Hz tone burst in 95 dBnHL. Results: In intervention group, cVEMP amplitudes increased from 41.86 to 55.71 μV and p13 and n23 latencies decreased from 13.81 and 22.61 to 13.32 and 21.69 ms, respectively. Also thresholds decreased from 85.52 to 81.71dBnHL. All changes were statistically significant (p< 0.05). Conclusion: The improvement of VEMP parameters following consumption of creatine supplement is likely due to increased sensitivity of saccule and vestibulocolic reflex pathway in normal subjects and maybe beneficial to patients with vestibular disorders.

کلیدواژه‌های انگلیسی مقاله

نویسندگان مقاله	وحید مرادی \| vahid moradi department of audiology, school of rehabilitation, tehran university of medical sciences, tehran, iran سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences) منصوره عادل قهرمان \| mansoureh adel ghahraman department of audiology, school of rehabilitation, tehran university of medical sciences, tehran, iran سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences) اکرم پوربخت \| akram pourbakht department of audiology, faculty of rehabilitation sciences, iran university of medical sciences, tehran, iran سازمان اصلی تایید شده: دانشگاه علوم پزشکی ایران (Iran university of medical sciences) شهره جلایی \| shohreh jalaie biostatistics, school of rehabilitation, tehran university of medical sciences, tehran, iran سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences) صوفیا نقدی \| soufia naghdi department of physiotherapy, school of rehabilitation, tehran university of medical sciences, tehran, iran سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

نشانی اینترنتی	http://avr.tums.ac.ir/index.php/avr/article/view/25
فایل مقاله	فایلی برای مقاله ذخیره نشده است
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زبان مقاله منتشر شده	en
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نوع مقاله منتشر شده	Research Article(s)

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