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Auditory and Vestibular Research، جلد ۲۱، شماره ۱، صفحات ۴۶-۵۳
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Auditory brainstem responses in children treated with cisplatin |
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| چکیده انگلیسی مقاله |
Background and Aim: In view of improvement in therapeutic outcome of cancer treatment in children resulting in increased survival rates and the importance of hearing in speech and language development, this research project was intended to assess the effects of cisplatin group on hearing ability in children aged 6 months to 12 years. Methods: In this cross-sectional study, hearing of 10 children on cisplatin group medication for cancer who met the inclusion criteria was examined by recording auditory brainstem responses (ABR) using the three stimulants of click and 4 and 8 kHz tone bursts. All children were examined twice: before drug administration and within 72 hours after receiving the last dose. Then the results were compared with each other. Results: There was a significant difference between hearing thresholds before and after drug administration (p< 0.05). Right and left ear threshold comparison revealed no significant difference. Conclusion: Ototoxic effects of cisplatin group were confirmed in this study. Insignificant difference observed in comparing right and left ear hearing thresholds could be due to small sample size. Auditory brainstem responses test especially with frequency specificity proved to be a useful method in assessing cisplatin ototoxicity. |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
مهسا بخیت | mahsa bakhit
department of audiology, faculty of rehabilitation, tehran university of medical sciences, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
اکرم پوربخت | akram pourbakht
department of audiology, faculty of rehabilitation, tehran university of medical sciences, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
معصومه روزبهانی | masoumeh rouzbahani
clinic of hematology and oncology of children, ali asghar hospital, tehran university of medical sciences, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
شهلا انصاری | shahla ansari
department of rehabilitation management, faculty of rehabilitation, tehran university of medical sciences, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
محمد کمالی | mohammad kamali
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| نشانی اینترنتی |
http://avr.tums.ac.ir/index.php/avr/article/view/445 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Research Article(s) |
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