Journal of Pediatrics Review، جلد ۶، شماره ۱، صفحات ۳۶-۴۳

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عنوان انگلیسی Endolysins of Bacteriophages as an Anti-Methicillin Resistant Staphylococcus aureus Infection in Children: A Narrative Review
چکیده انگلیسی مقاله Context: Spread of Methicillin-resistant Staphylococcus aureus (MRSA) can cause serious and sometimes fatal diseases especially in children. Outbreaks and increasing the prevalence of antibiotic-resistant MRSA at pediatric hospital calls for the development of novel preservation techniques. Endolysins and bacteriophages have been used successfully to control bacterial infections in children. Endolysins were considered as a useful treatment especially for the pathogens without disturbing the normal flora, the low chance of bacterial resistance, and their ability to kill colonizing pathogens on mucosal surfaces. Herein, we aimed to review the effectiveness of endolysins of bacteriophage for controlling methicillin-resistant Staphylococcus aureus infections in children. Evidence Acquisition: This review was performed by searching studies indexed in international databases including PubMed, Scopus, Web of Science, Science Direct, as well as Google Scholar published from 2000 until 2016. Results: Experimental data show that endolysins of Staphylococcus aureus bacteriophage can be used to combat methicillin-resistant Staphylococcus aureus infections in children. Conclusions: Endolysins of bacteriophages could be effective for controlling a variety of methicillin-resistant Staphylococcus aureusinfections.
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نویسندگان مقاله گلنار رحیم زاده | golnar rahimzadeh


پوریا گیل | pooria gill


محمد صادق رضایی | mohammad sadegh rezai
pediatric infectious diseases research center, mazandaran university of medical sciences, sari, ir iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مازندران (Mazandaran university of medical sciences)


نشانی اینترنتی http://jpr.mazums.ac.ir/browse.php?a_code=A-10-30-76&slc_lang=en&sid=en
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/268/article-268-565870.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده عفونی اطفال
نوع مقاله منتشر شده مرور نقلی
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